Brilliant but brusque renowned surgeon Martin Best leaves his lucrative career in Boston to become the general practitioner in the small seaside village of Port Wenn, Maine.
Martin encounters his childhood bully and identifies a contagious disease, forcing him to cancel the town's monthly bean supper-much to the locals' anger.
On the eve of Port Wenn High School's baseball team's playoff game, the town is furious with Martin when he accidentally breaks the arm of their star player; Elaine moves into Martin's waiting room after fighting with her mom.
Martin's abrupt behavior triggers a town blackout during a wellness check. Residents face hardships while Martin bonds with a boy. Louisa and Mark have an intimate moment.
On the eve of Port Wenn's annual blueberry festival, Martin treats a local man who has apparently become blue from eating too many blueberries; Martin is disturbed by Aunt Sarah's lack of attention to her health.
Port Wenn's annual "Blood Factory" event honors a gory horror novel set in town. Martin must hide his severe blood phobia while treating a seriously ill Louisa. The town buzzes with rumors that the novel's author may attend.
Port Wenn goes on high alert when a corpse is found in the town bog. Martin's autopsy reveals murder. His solo investigation leads to a startling self-discovery while the neighborhood watch becomes a gossip mission.
Martin's parents arrive unannounced, raising concerns about his father Robert's health. While Louisa temporarily leads the school during Spirit Week amid closure threats, Martin and Robert must work together to operate on a patient.
Port Wenn locks down after a patient with fleas raises plague concerns. Martin faces town gossip about him and Louisa. Aunt Sarah feels betrayed by Greg and George. Louisa has an epiphany.
Martin doubts Port Wenn's warm Norwegian sister-city visitors while Louisa sees a specialist who's Martin's ex. Greg thinks he's passing tiny people, and Mark shows concerning symptoms needing attention.
Port Wenn residents learn the truth about their Norwegian sister city deal. Martin faces his blood phobia exposure, delivers a baby, and encounters his ex. Louisa gets medical results. Al and Elaine face their uncertain future.
