Liza Powel O'Brien has been married to Conan O'Brien since 12 January 2002. They have two children.

Conan O'Brien: The Kennedy Center Mark Twain Prize for American Humor

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The Biggest Movies and TV Coming in September

"The Gentlemen" and "Slow Horses" return this fall, while the "Reacher" spin-off series "Neagley" makes its debut. See our guide of the biggest Fall TV and streaming releases.

2026 Fall TV and Streaming Watch Guide

&quot;The Gentlemen&quot; and &quot;Slow Horses&quot; return this fall, while the &quot;Reacher&quot; spin-off series &quot;Neagley&quot; makes its debut. See our guide of the biggest Fall TV and streaming releases.

Get a closer look at these actors from their many TV and streaming series roles.

Streaming Stars, Then and Now

Liza Powel O'Brien in Late Night with Conan O'Brien (1993)

Hilton Koch and Liza Powel O'Brien in Late Night with Conan O'Brien (1993)

Neve O'Brien, Beckett O'Brien, and Liza Powel O'Brien in Conan O'Brien: The Kennedy Center Mark Twain Prize for American Humor (2025)

Conan O'Brien and Liza Powel O'Brien at an event for The Oscars (2026)

Conan O'Brien and Liza Powel O'Brien at an event for The Oscars (2025)

Conan O'Brien in Conan O'Brien: The Kennedy Center Mark Twain Prize for American Humor (2025)

Liza Powel O'Brien

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