- Tested for the role of Edward Cullen in Twilight (2008).
- Has two brothers, James Franco and Tom Franco.
- Engaged to Alison Brie since August 2015. They married in 2017.
- Childhood hero was Roald Dahl.
- While attending USC he wrote, directed and edited comedy shorts in the early days of Funny or Die.
- Began his relationship with actress Alison Brie c. 2012.
- Dave's father was of half-Portuguese and half-Swedish descent, with his Portuguese roots in the Madeira islands. Dave's mother is from an Ashkenazi Jewish family (from Russia, Germany, Poland, and Lithuania).
- Dave and his brother James Franco have played famous comic book characters from opposing companies. James played Harry Osborn, best friend of Marvel Comics' Peter Parker/Spider-Man and son of his arch nemesis, The Green Goblin, in Sam Raimi's film trilogy. Dave voiced Edward Nygma/The Riddler, iconic nemesis of DC Comics' Batman in the series Young Justice: Legacy (2013). Dave more recently provided the voice for Tony Stark/Iron Man in Avengers Academy (2016), alongside his then-fiancée Alison Brie, meaning that he has now played characters from both DC and Marvel.
- Son of Betsy Franco.
- Has two cats named Harry and Arturo. The cats belonged to his brother James Franco until he moved to New York, and gave the two cats to Dave.
- Graduated from the University of Southern California.
- On his father's side, he is the grandson of Daniel Franco Jr. and Marjorie J. (Peterson) Franco, a published author of young adult books. On his mother's side, he is the grandson of Daniel Verne (born Daniel S. Verovitz) and Marjorie "Mitzie" Levine. One of Dave's maternal great-grandfathers, Emanuel "Manuel" V. Levine, was a prominent judge in Cleveland, Ohio.
- Two of his movies, 22 Jump Street (2014) and Warm Bodies (2013), feature the same two songs on their respective soundtracks; John Waite's "Missing You" from 1984 and "Midnight City" by M83 from 2011.
- Lives in Hollywood. (2010)
- Took Molly (MDMA) together with his wife Brie the night they met.
- Born at 9:18 PM (PDT).
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