- Her favorite actor is William H. Macy.
- Her mother is a twin, her father is a twin, and she has twin siblings.
- Auditioned for Akeelah and the Bee (2006) 5 times. Director was convinced by the emotion in her crying the 5th time around.
- Trained for 7 weeks with a professional quarterback preparing for her role in The Longshots (2008).
- Was in two movies where Queen Latifah played her mother - Joyful Noise (2012) and Ice Age: Continental Drift (2012).
- In 2014 Keke Palmer made history as the first African American woman and the youngest person to play Cinderella on Broadway. She took over the role after Carly Rae Jepson left the show. Keke made her debut in "Cinderella" on September 9, 2014 and played the role until the show closed on January 3, 2015.
- She hosted her own talk show series Just Keke at just twenty years old, making her the youngest talk show host in television history.
- She resides in Los Angeles, CA.
- Is close friends with Carlysia Levert, daughter of the late Gerald Levert.
- Was invited to join the actor's branch of the Academy of Motion Picture Arts & Sciences in 2023.
- Friends with Tyler Perry.
- Sister of Lawrence Palmer and Lawrencia Palmer.
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