- Melisanne Russo is known for It's Me, Matthew! (2008), In Search of Myster Ey (2008) and Burn Out the Day (2010).
- She worked on the film Trust the Man (2005) Bart Freundlich chose her to play a nurse. She is credited on the DVD side B where her scene with David Duchovny appears.
- Auditioned for Will Speck for a part in the Jennifer Aniston film The Switch (2010) She booked the part but when it came time for shooting production kept on changing the shooting dates and the scene never got filmed.
- She has appeared several times on Vh1's _"Celebrity Rehab with Dr. Drew" (2008)_ playing one of several drug addicts. It is a PSA cast by Liz Lewis.
- Rehearsing for a play "Patriots" by Naomi McDougall Jones, New York, November 4th-8th
- Performing with Frizzi & Lazzi the Olde Time Italian-American Music and Theatre Company in Yesterdays Sky written by 'Angela Rago'
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