- She does not drive (due to a personal phobia, she never learned) and mostly relies on friends and public transport.
- Has a twin sister named Amy.
- While working on The Incredibles (2004) she wrote the novel "Assassination Vacation" in which she traveled to the locations where presidents were assassinated.
- Suffers from celiac disease, an intolerance to wheat, barley, and rye gluten.
- Has voiced her dissatisfaction with Incredibles 2 (2018), saying that although she loved voicing the character of Violet Parr again, she thought the final product was "mediocre" and criticized how it handled her character.
- Contributes to PRI's This American Life radio program.
- Is a friend and frequent traveling companion of Bennett Miller. She talks about him in her book "Assassination Vacation" and his photo portrait of her appears on all the back covers of her books.
- Her favorite movies that she listed are The Nightmare Before Christmas, Run Lola Run, The Great Escape, Edward Scissorhands, Pan's Labyrinth and Spider-Man 2.
- Has expressed interest in screenwriting.
- Is a fan of English rock musician PJ Harvey.
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