- The "Batman" character, Harley Quinn (real name Harleen Quinzell), was created just for Arleen by her friend, writer Paul Dini.
- She is said to provide many of the voices of radio callers on Frasier (1993), which her husband produces, only to be dubbed out later by a celebrity's voice.
- She and her husband, Christopher Lloyd, have two children: Eli Lloyd and Owen Lloyd.
- The original voice (and inspiration) for Harley Quinn.
- Her two favorite episodes of the "Batman: The Animated Series" are 'Harley and Ivy' & 'Harley's Holiday'.
- As "Arlene: Sorkin, she performed as the sexiest member of the Manhattan-based female comedy troupe in the early 1980s known as The High-Heeled Women, who were managed/produced by Warren Leight.
- Daughter of Irving Sorkin.
- Friend of Dana Delany.
- Sister-in-law of Stephen Lloyd.
- Daughter-in-law of David Lloyd.
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