- Twin sister of Isabella Rossellini.
- Daughter of Roberto Rossellini and Ingrid Bergman
- Has remembered her father's and her mother's film work in various essays and articles of both personal and cinematic nature.
- Her studies and research specialize in the works of Petrarch and Dante.
- Was extremely shy as a little girl, and even today rarely gives interviews.
- In 1995, was a professor of Italian Renaissance literature at Columbia University where she also received her doctorate.
- In 2009, assisted in the campaign of her husband Richard Aborn for District Attorney (D) of Manhattan, New York City.
- Has always lived near her twin sister between Rome, Paris, and New York.
- Initially teaching literature at Columbia, she has also taught at NYU, Princeton and Harvard universities.
- Ex-sister-in-law of Martin Scorsese.
- Sister of Robertino Rossellini, and half-sister of Pia Lindström (different father) and Renzo Rossellini (different mother).
- Niece of Renzo Rossellini.
- Mother of Francesca Aborn and Tommaso Rossellini.
- Isotta weighed 7 lbs 1 oz at birth according to her and sister Isabella's birth announcement in the milestones Column of Time Magazine's June 30th 1952 issue.
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