- Most of his films deal with controversial issues and have political messages.
- Was a supporter of the Italian Communist Party (PCI).
- Father of actress Carolina Rosi.
- Member of the 'Official Competition' jury at the 54th Venice International Film Festival in 1997.
- Studied law at the University of Naples.
- After Goffredo Alessandrini withdrew from Anita Garibaldi (1952), he made his debut as director.
- His father worked for a ship company.
- His wife Giancarla Mandelli , sister of Mariuccia Mandelli Krizia died in an apartment fire caused by a cigarette.
- Father-in-law of Luca De Filippo.
- Good friends with Italian President Giorgio Napolitano.
- Brother-in-law of Mariuccia Mandelli best known as Krizia.
- In the fifties and the early sixties he was the partner of actress Nora Ricci. They had a daughter, Francesca, who tragically died when she was fifteen in a car accident, in which Francesco Rosi was seriously injured (on 18 January 1969, near Ferentino).
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