- Said if he wasn't a actor he would love to be a pediatrician.
- Underwent a resection of his small intestine as the result of a football injury, so he can't gain weight.
- His mom left his family when he was only 10 years old, which he says helps him to relate to his character Lucas Scott on One Tree Hill (2003).
- Was originally up for the role of Ryan Atwood on The O.C. (2003), but turned it down for Lucas Scott on One Tree Hill (2003).
- His father Rex works as an air traffic controller.
- His wife, Sarah Roemer, gave birth to their first child, a son, on May 31, 2015, and to their second child, a daughter, in March 2017.
- Has three brothers (Rex, Nick, and Brandon), one sister (Shannon) and one half-brother (Tyler).
- Modeled for Skechers, Tommy Hilfiger and Gucci.
- Got an accidental 'nose job' during his earlier modeling career! He was 'jumped' in a fast food restaurant and got his nose broken and had to have surgery. If you look closely, you can see the difference between his nose now and back then, because he had to get it fixed and it couldn't be constructed to the way it was.
- His favorite book is "Catcher in the Rye" by J.D. Salinger.
- His first job was when he was 10 delivering newspapers, then when he turned 14 he started working as a janitor at the local doughnut shop.
- His favorite movie is Fight Club (1999).
- Ended his seven-year engagement to Kenzie Dalton, a 2006 Graduate of John T. Hoggard High School in Wilmington, North Carolina, in September 2013.
- He has three dogs. A shepherd/wolf mix named Joe, which he takes everywhere with him and a guard dog named Axel. He and Kenzie share a Chihuahua/Pomeranian mix named TumTum.
- Chad and three of his One Tree Hill (2003) co-stars were on Dawson's Creek (1998) with him; Hilarie Burton Morgan (who plays "Peyton Sawyer"), Lee Norris (who plays "Mouth McFadden") and Colin Fickes (who plays "Jimmy Edwards").
- Chad Michael Murray married Sophia Bush on April 16, 2005 in Santa Monica, California. In September 2005, after five months of marriage, they announced their separation. Bush filed papers seeking an annulment on the grounds of fraud in February 2006. The divorce court denied her petition, and granted her and Murray a divorce, in December 2006, instead.
- His favorite television show is The Simpsons (1989).
- His favorite fashion accessory is a hemp necklace that his father gave him and a necklace made for him from Kenzie.
- 26 September 2005: Sophia Bush announced their separation.
- His hobbies are: Going to the gym, pickup basketball and football.
- His father is of English, German, Swiss-German, and Irish descent and his mother is of Polish ancestry.
- He loves listening to the music of Frank Sinatra and James Brown.
- Ranked #22 in TV Guide's list of "TV's 25 Greatest Teen Idols" (23 January 2005 issue).
- Wore a Ralph Lauren Black Label Suit in his April 2005 wedding to Sophia Bush.
- Chad means: warlike, warrior.
- Of Clan Murray.
- Ex-son-in-law of Charles William Bush.
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