- Cameron was diagnosed at 2-1/2 years old with Legg-Pertheas disease, which is a degeneration of the hip bones, and for which he spent six months in the hospital, then the next 3-1/2 years on crutches, wearing a steel A-frame brace on his legs.
- Graduated from McGill University (in Montreal) with a Bachelors in civil engineering
- Joined Entertainment Tonight (1981) as a full-time correspondent and weekend co-anchor [April 5, 2015].
- Father, with Vanessa Mathison, of daughter, Leila Mathison, born on 7 July 2006.
- Cameron and his wife, Vanessa, welcomed their first child, a boy named Lucas Arthur Mathison, on April 20, 2003, weighing in at 6 pounds, 13 ounces.
- June 2000 Voted one of America's 100 most eligible bachelors in People Magazine.
- Father, with Vanessa Mathison, of son Lucas Mathison (Lucas Arthur Mathison), born on April 20, 2003.
- Appeared on the cover of Playgirl magazine, February 1999.
- attended Thornlea High School in Thornhill, Ontario, Canada.
- Older brother is Scott Mathison.
- Good friends with Rebecca Budig. Was the photographer at her wedding to Bob Guiney.
- Lost his home due to the L.A. fires of January 2025.
- Eden Riegel is married to Andrew Miller, one of his childhood friends.
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