15 wins & 27 nominations
- 2019 Nominee Critics Choice Award
- Best Supporting Actress in a Movie or Limited Series
- 2023 Winner Primetime Emmy
- Outstanding Guest Actress in a Comedy Series
- 2018 Nominee Primetime Emmy
- Outstanding Supporting Actress in a Limited Series or Movie
For "The Assassination of Gianni Versace" - 2017 Nominee Primetime Emmy
- Outstanding Supporting Actress in a Comedy Series
For playing: "Shelly Pfefferman". - 2016 Nominee Primetime Emmy
- Outstanding Supporting Actress in a Comedy Series
For playing: "Shelly Pfefferman".
- 2016 Nominee Golden Globe
- Best Performance by an Actress in a Supporting Role in a Series, Limited Series or Motion Picture Made for Television
- 2016 Nominee Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Alexandra Billings · Carrie Brownstein · Jay Duplass · Kathryn Hahn · Gaby Hoffmann · Cherry Jones · Amy Landecker · Hari Nef · Emily Robinson · Jeffrey Tambor - 2008 Nominee Actor
- Outstanding Performance by an Ensemble in a Comedy Series
Shared with: Alan Dale · America Ferrera · Christopher Gorham · Mark Indelicato · Ashley Jensen · Eric Mabius · Becki Newton · Ana Ortiz · Tony Plana · Rebecca Romijn · Michael Urie · Vanessa Williams
- 2007 Nominee TV Land Award
- The "She Works Hard for the Money" Award (Favorite Working Mom)
- 2018 Winner OFTA Television Award
- Best Supporting Actress in a Motion Picture or Limited Series
For the second season entitled "The Assassination of Gianni Versace". 
2018 Winner OFTA TV Hall of Fame- Actors and Actresses
- 2020 Nominee WIN Award
- Outstanding Actress Made for Television Movie / Mini-Series
- 2018 Nominee Gold Derby TV Award
- Ensemble of the Year
For "The Assassination of Gianni Versace"Shared with: Joanna Adler · Annaleigh Ashford · Jon Jon Briones · Darren Criss · Penélope Cruz · Mike Farrell · Jay R. Ferguson · Cody Fern · Max Greenfield · Ricky Martin · Dascha Polanco · Edgar Ramírez · Finn Wittrock - 2018 Winner Gold Derby TV Award
- Movie/Limited Series Supporting Actress
For "The Assassination of Gianni Versace"
- 2020 Nominee Queerty
- Straight Best Friend
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