- A descendant of the philosopher David Hume.
- Was the chief writer of MGM's :'Tarzan" movies in the 1930s and is credited with having suggested Johnny Weissmuller for the starring role. Remained under contract with MGM until 1957.
- Though sometimes referred to as the brother of English actress Benita Hume, Cyril Hume was actually born in New Rochelle, NY, the son of Thomas and Harriet Hume. His siblings were Mary, Nelson, Alexander, Constance, Dorothy, and Raphael, a noted architect.
- Brother-in-law of George Sanders.
- During the early 1930s, he and wife Helen Chandler lived in the "French Pavilion" house of the French Village housing development in Hollywood, off of Highland Avenue, just below Whitley Heights and across the street from the Hollywood Bowl. The unique set of homes, by Walter S. and F. Pierpont Davis, were razed in 1952 to make way for the Hollywood Freeway.
- Was a graduate of Yale University, where he edited the campus humor magazine 'The Yale Record'.
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