- Has known J.J. Abrams since they were in kindergarten. Greg has gotten parts in almost every project J.J. works on.
- One of his children has epilepsy, which inspired Grunberg to take an active role in raising awareness of the neurological disorder and raising funds for research.
- Came up with the concept for a location-aware coupon application for the iPhone called "Yowza!!" along with business partners August Trometer and Rick Yaeger.
- Created and ran a successful frozen yogurt delivery service.
- Founder of Band From TV Global Charity Trust. Drummer of Band From TV, comprised of other television stars including: ABC's Bob Guiney, actor Hugh Laurie, actor James Denton and actress Bonnie Somerville.
- Was originally set play Detective Wallace MacTee in Hero Wanted (2008) alongside Ray Liotta and Cuba Gooding Jr. but was forced to drop out at the last minute due to scheduling conflicts with his role on Heroes (2006).
- Is the Chair of the National Walk for Epilepsy "2008".
- Acted in several high-profile television commercials early on in his career, including one that was so memorable it landed him on "The Tonight Show."
- Has three sons with his wife: Jake (b. 1996), Ben (b. 1999) and Sam (b. 2003).
- Grunberg, whose child suffers from epilepsy, demanded an apology from film director Brett Ratner because his film Tower Heist (2011) featured an offensive joke about epileptic seizures.
- Auditioned for the role of Fred Flintstone in The Flintstones in Viva Rock Vegas (2000).
- Both Greg Grunberg and Masi Oka were in 2002's "Austin Powers in Goldmember" and never shared any scenes together. That would change in 2006 when they both went on to star in their respective roles in "Heroes".
- Younger brother of Brad Grunberg.
- Arrived in Singapore to promote Season 2 of Heroes (2006), as part of the World Tour [31 August 2007]. (August 2007)
- Born on exactly the same date as Debbe Dunning (of "Home Improvement" fame).
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