- Discovered by Bing Crosby whose production company made Ben Casey (1961)
- He lost a month-long struggle against pancreatic cancer on the night of March 11, 1996, at UCLA Medical Center in Los Angeles. He had been hospitalized for 11 days.
- He had a twin brother, Bob Zoino.
- Production of Hammerhead (1968) was held up for a few weeks when he broke his heel bone, according to David Prowse on his website. Most of his standing, walking and running scenes were done by his double.
- Declined the part of "The Doctor" in Airplane! (1980).
- Possessed of a pleasant, light tenor voice, he recorded half a dozen albums for Decca records at the height of his Ben Casey (1961) popularity, the first of which, "Vincent Edwards Sings," spent several weeks on the top-20 Billboard LP charts in early 1962.
- He was the favorite actor of Bo Jackson's mother. She named her son Vince Edward Jackson.
- Vince Edwards's first role was in "Mr. Universe." Harry Landers, who co-starred in "Ben Casey," was also in "Mr. Universe.".
- Alumnus of the AADA (American Academy of Dramatic Arts), Class of 1950.
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