- In 1953 he won second prize in composition for the Belgian Queen Elisabeth competition.
- Aged ten he entered the Paris Conservatoire and completed his musical training in theory, piano and composition, taking in Nadia Boulanger's accompaniment class.
- In 1952 he won the Premier Second Grand Prix de Rome.
- Known for his collaboration with French poet and singer-songwriter Léo Ferré.
- In 1952 he won the Premier Second Grand Prix de Rome and the following year he won second prize in composition for the BelgianQueen Elisabeth competition.
- As a composer he wrote mostly for brass and especially trombone.
- He is mostly known by general public in France today for this body of work.
- In August 2006, he took part in the reconstitution of the Big Band of the Olympia (twenty-five musicians), during the Jazzaparc festival in Aveyron.
- Jean-Michel Defaye was a French pianist, composer, arranger and conductor known for his collaboration with French poet and singer-songwriter Léo Ferré.
- He is the composer of the songs in the animated television series Bonne nuit les petits and Colargol .
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