Mayme Clayton was born on 4 August 1923 in Van Buren, Arkansas, USA. She was married to Andrew Lee Clayton. She died on 13 October 2006 in Inglewood, California, USA.
Collector of African American memorabilia, including rare books, photographs, films, and other miscellaneous artifacts. Her son Avery used the collection as the foundation of the Mayme A. Clayton Library and Museum.
