- An important Vitagraph Company star in the 1910's, Barker was famous for her hourglass figure.
- Served as the costume director for the original cast production of "No, No Nanette" (1926). Also appeared on Broadway as an actress.
- Barker began appearing in films in 1918, debuting in Money Mad. Her second film appearance in Peck's Bad Girl (1918) was praised by Variety, which noted: "Corinne Barker as the wily Hortense could not have been better cast.".
- After making the transition to theater in the 1920s, Barker began working as a costume designer in Manhattan, working under Vincent Youmans.
- She was educated at the Academy of the Sacred Heart in Salem.
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