- Isay Alvarez is known for Maalaala Mo Kaya (1991), La visa loca (2005) and A Soldier's Heart (2020). She is married to Robert Seña.
- SpouseRobert Seña(? - present)
- A member of the quartet, Ang4gettables. She replaced Nanette Inventor who, together with Mon David, left the group. Together with then-newcomer Bimbo Cerudo, she completed the second line-up of the group with original members, Pinky Marquez and George Javier. The second line-up is called Ang4. The group has traveled abroad extensively for shows bringing music and goodwill to Filipinos abroad.
- While having theater engagements, Isay is also doing rounds of lounge performances in five-star hotels.
- Can dance, sing and act.
- A product of local musical productions staged exclusively at the Manila Metropolitan Theatre and Cultural Center of the Philippines at its peak in 1980s when quality musicales were being produced.
- In 2003, she played Nimia in CCP's production of Himala, the stage musical based on the hit movie Miracle (1982).
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