10 wins & 33 nominations
- 2007 Winner Primetime Emmy
- Outstanding Supporting Actress in a Drama Series
For playing: "Izzie Stevens".
- 2008 Nominee Golden Globe
- Best Performance by an Actress in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television
- 2007 Nominee Golden Globe
- Best Performance by an Actress in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television
- 2006 Winner Satellite Award
- Best Ensemble, Television
Shared with: Justin Chambers · Eric Dane · Patrick Dempsey · T.R. Knight · Sandra Oh · James Pickens Jr. · Ellen Pompeo · Sara Ramirez · Kate Walsh · Isaiah Washington · Chandra Wilson
- 2024 Nominee Leo
- Best Dramatic Series
Shared with: Maggie Friedman · Jonathan Shore · Stephanie Germain · Michael Spiller · Shawn Williamson · Arielle Boisvert
2011 Nominee People's Choice Award- Favorite Movie Actress
- 2010 Winner People's Choice Award
- Favorite TV Drama Actress
- 2008 Winner People's Choice Award
- Favorite Female TV Star
- 2012 Nominee Razzie Award
- Worst Ensemble
Shared with: Robert De Niro · Josh Duhamel · Jessica Biel · Halle Berry · Ludacris · Zac Efron · Abigail Breslin · Jon Bon Jovi · Ashton Kutcher · Hector Elizondo · Sarah Jessica Parker · Sofía Vergara · Michelle Pfeiffer · Hilary Swank · Seth Meyers · Til Schweiger · Lea Michele
- 2008 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Justin Chambers · Eric Dane · Patrick Dempsey · T.R. Knight · Chyler Leigh · Sandra Oh · James Pickens Jr. · Ellen Pompeo · Sara Ramirez · Elizabeth Reaser · Brooke Smith · Kate Walsh · Isaiah Washington · Chandra Wilson - 2007 Winner Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Justin Chambers · Eric Dane · Patrick Dempsey · T.R. Knight · Sandra Oh · James Pickens Jr. · Ellen Pompeo · Sara Ramirez · Sarah Utterback · Kate Walsh · Isaiah Washington · Chandra Wilson - 2006 Nominee Actor
- Outstanding Performance by an Ensemble in a Drama Series
Shared with: Justin Chambers · Patrick Dempsey · T.R. Knight · Sandra Oh · James Pickens Jr. · Ellen Pompeo · Kate Walsh · Isaiah Washington · Chandra Wilson
- 2010 Winner ShoWest Award
- Female Star of the Year
- 1995 Nominee Young Artist Award
- Best Performance by a Young Actress Starring in a Motion Picture
- 2013 Winner EDA Special Mention Award
- Actress Most in Need of a New Agent
Tied with Reese Witherspoon for This Means War (2012). - 2011 Nominee EDA Special Mention Award
- Actress Most in Need of a New Agent
- 2009 Nominee EDA Special Mention Award
- Actress Most in Need of a New Agent
- 2015 Nominee BTVA Feature Film Voice Acting Award
- Best Female Lead Vocal Performance in a Feature Film
As the voice of "Andie".
- 2007 Nominee Gold Derby TV Award
- Ensemble of the Year
Shared with: Justin Chambers · Eric Dane · Patrick Dempsey · T.R. Knight · Sandra Oh · James Pickens Jr. · Ellen Pompeo · Sara Ramirez · Kate Walsh · Isaiah Washington · Chandra Wilson - 2006 Nominee Gold Derby TV Award
- Ensemble of the Year
Shared with: Justin Chambers · Patrick Dempsey · T.R. Knight · Sandra Oh · James Pickens Jr. · Ellen Pompeo · Kate Walsh · Isaiah Washington · Chandra Wilson
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