6 wins & 36 nominations
- 1998 Nominee American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1991 Nominee American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1990 Nominee American Comedy Award
- Funniest Actress in a Motion Picture (Leading Role)
- 1990 Nominee American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1989 Nominee American Comedy Award
- Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication
- 1998 Nominee Primetime Emmy
- Outstanding Lead Actress in a Comedy Series
For playing: "Veronica Chase". - 1997 Nominee Primetime Emmy
- Outstanding Supporting Actress in a Miniseries or a Special
For playing: "Rose Marie Clericuzio". - 1994 Winner Primetime Emmy
- Outstanding Lead Actress in a Miniseries or a Special
For playing "Sally Goodson".
- 1998 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 1995 Nominee Golden Globe
- Best Performance by an Actress in a Miniseries or Motion Picture Made for Television
- 1993 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 1992 Nominee Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 1991 Winner Golden Globe
- Best Performance by an Actress in a Television Series - Comedy or Musical
- 1997 Nominee Golden Satellite Award
- Best Actress in a Miniseries or a Motion Picture Made for Television
1998 Winner People's Choice Award- Favorite Female Performer in a New Television Series
- 1993 Nominee People's Choice Award
- Favorite Female TV Performer
- 1992 Nominee People's Choice Award
- Favorite Female TV Performer
- 1991 Winner People's Choice Award
- Favorite Female TV Performer
- 1990 Nominee People's Choice Award
- Favorite Female TV Performer
- 1991 3rd Place Bravo Otto Germany
- Best Actress (Schauspielerin)
- 1990 3rd Place Bravo Otto Germany
- Best Actress (Schauspielerin)
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